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Authors: Weinstock LB, Brook JB, Walters AS, Goris A, Afrin LB, Molderings GJ PMID: 34563706 PMCID: PMC8459548 DOI: 10.1016/j.ijid.2021.09.043 Abstract Objectives: Hyper-inflammation caused by COVID-19 may be mediated by mast cell activation (MCA) which has also been hypothesized to cause Long-COVID (LC) symptoms. We determined prevalence/severity of MCA symptoms in LC. Methods: Adults in LC-focused [...]
Categories: I-RECOVER Post-Vaccine
Tags: long COVID, mast cell activation
Authors: Zuo T, Wu X, Wen W, Lan P PMID: 34560321 PMCID: PMC8478109 DOI: 10.1016/j.gpb.2021.09.004 Abstract Since the outset of the coronavirus disease 2019 (COVID-19) pandemic, the gut microbiome in COVID-19 has garnered substantial interest, given its significant roles in human health and pathophysiology. Accumulating evidence is unveiling that the gut microbiome is broadly altered [...]
Categories: I-RECOVER Post-Vaccine
Tags: COVID-19, Gut Microbiota
Authors: Krause DN, Warfvinge K, Haanes KA, Edvinsson L PMID: 34545218 DOI: 10.1038/s41582-021-00544-2 Abstract Migraine is ranked as the second highest cause of disability worldwide and the first among women aged 15-49 years. Overall, the incidence of migraine is threefold higher among women than men, though the frequency and severity of attacks varies during puberty, [...]
Categories: I-RECOVER Post-Vaccine
Authors: Hurmach V, Platonov MO, Prylutska SV, Scharff P, Ritter U PMID: 34493768 PMCID: PMC8423725 DOI: 10.1038/s41598-021-97268-6 Abstract Based on WHO reports the new SARS-CoV-2 coronavirus is currently widespread all over the world. So far > 162 million cases have been confirmed, including > 3 million deaths. Because of the pandemic still spreading across the [...]
Categories: I-RECOVER Post-Vaccine
Tags: COVID-19, Fullerenes
Authors: Arthur JM, Forrest JC, Boehme KW, Kennedy JL, Owens S, Liu J PMID: 34478478 PMCID: PMC8415618 DOI: 10.1371/journal.pone.0257016 Abstract Background: Activation of the immune system is implicated in the Post-Acute Sequelae after SARS-CoV-2 infection (PASC) but the mechanisms remain unknown. Angiotensin-converting enzyme 2 (ACE2) cleaves angiotensin II (Ang II) resulting in decreased activation of [...]
Categories: I-RECOVER Long Covid, I-RECOVER Post-Vaccine
Tags: ACE2 protein, autoantibodies, COVID-19
Authors: Chen BM, Cheng TL, Roffler SR PMID: 34469112 DOI: 10.1021/acsnano.1c05922 Abstract Polyethylene glycol (PEG) is a flexible, hydrophilic simple polymer that is physically attached to peptides, proteins, nucleic acids, liposomes, and nanoparticles to reduce renal clearance, block antibody and protein binding sites, and enhance the half-life and efficacy of therapeutic molecules. Some naïve individuals [...]
Categories: I-RECOVER Post-Vaccine
Authors: Dacasin AB, Diagono DM, So PK, Bautista VR, Bucu ML, Bueno PR DOI: 10.22271/phyto.2021.v10.i6a.14254 Abstract This review summarizes the background of Cocos nucifera, the benefits of the isolated virgin coconut oil (VCO), such as its potential as an adjunctive treatment for COVID-19, and its pharmacological effects, including antiviral and anti-inflammatory properties that could be [...]
Categories: I-RECOVER Post-Vaccine
Tags: COVID-19
Authors: Oliaei S, Mehrtak M, Karimi A, Noori T, Shojaei A, Dadras O PMID: 34412709 PMCID: PMC8374420 DOI: 10.1186/s40001-021-00570-2 Abstract Background: Oxygenation serves as a cornerstone in the treatment of COVID-19, and several methods have been extensively studied so far. Herein, we aimed to systematically review the studies discussing hyperbaric oxygen therapy (HBOT) to examine [...]
Categories: I-RECOVER Post-Vaccine
Authors: Verma AK, Lavine KJ, Lin CY PMID: 34407340 PMCID: PMC8385564 DOI: 10.1056/NEJMc2109975 Abstract The Centers for Disease Control and Prevention recently reported cases of myocarditis and pericarditis in the United States after coronavirus disease 2019 (Covid-19) messenger RNA (mRNA) vaccination.1 In recently published reports, diagnosis of myocarditis was made with the use of noninvasive [...]
Categories: I-RECOVER Post-Vaccine
Authors: Gupta AK, Venkataraman M, Talukder M, Bamimore MA PMID: 34291720 DOI: 10.1080/09546634.2021.1959506 Abstract Background and objectives: Finasteride 1 mg/day is indicated for androgen-dependent conditions such as male androgenetic alopecia (AGA). Methods: The literature is comprehensively summarized on the pharmacodynamics, pharmacokinetics, mechanism of action, and metabolism of finasteride. Pairwise and network meta-analyses were performed to [...]
Categories: I-RECOVER Post-Vaccine
Tags: Finasteride