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Conclusions: The results of this case series suggest that high-dose oral famotidine is well tolerated and associated with improved patient-reported outcomes in non-hospitalised patients with COVID-19.
Categories: MATH+
Tags: COVID-19, Famotidine, PROMs, SARS-CoV-2
Daniel E Freedberg, Joseph Conigliaro, Timothy C Wang, Kevin J Tracey, Michael V Callahan, Julian A Abrams, Famotidine Research Group PMID: 32446698 PMCID: PMC7242191 DOI: 10.1053/j.gastro.2020.05.053 AbstractNo abstract available. Keywords: Histamine H2 Antagonists, Famotidine Source: https://pubmed.ncbi.nlm.nih.gov/32446698/ Archive: https://archive.is/wip/xU10m
Categories: MATH+
Authors: Zhang S, Liu Y, Wang X, Yang L, Li H, Wang Y PMID: 32887634 PMCID: PMC7471641 DOI: 10.1186/s13045-020-00954-7 Abstract Background: Critically ill patients diagnosed with COVID-19 may develop a pro-thrombotic state that places them at a dramatically increased lethal risk. Although platelet activation is critical for thrombosis and is responsible for the thrombotic events [...]
Categories: MATH+
Tags: ACE2 protein, COVID-19, SARS-CoV-2
Authors: Cheng HY, Jian SW, Liu DP, Huang WT, Lin HH PMID: 32356867 PMCID: PMC7195694 DOI: 10.1001/jamainternmed.2020.2020 Abstract Importance: The dynamics of coronavirus disease 2019 (COVID-19) transmissibility are yet to be fully understood. Better understanding of the transmission dynamics is important for the development and evaluation of effective control policies. Objective: To delineate the transmission [...]
Categories: MATH+
Tags: COVID-19
Authors: Ahmed AK, Albalawi YS, Shora HA, Abelseed HK, Al-Kattan AN. DOI:10.37179/rijed.000005 Abstract ABSTRACT COVID-19 emerged in Wuhan, China in December 2019, reached epidemic proportions and spread globally as a serious life-threatening pandemic. SARS- Cov-2 is the causative virus that causes severe acute respiratory distress, pneumonia, respiratory failure, and septic shock leading to increased mortality. [...]
Categories: I-CARE Early Covid, MATH+
Authors: Castillo ME, Costa LM, Barrios JM, Diaz JF, Miranda JL, Bouillon R et al. PMID: 32871238 PMCID: PMC7456194 DOI: 10.1016/j.jsbmb.2020.105751 Abstract Objective: The vitamin D endocrine system may have a variety of actions on cells and tissues involved in COVID-19 progression especially by decreasing the Acute Respiratory Distress Syndrome. Calcifediol can rapidly increase serum [...]
Categories: I-CARE Early Covid, MATH+
Tags: Calcifediol, COVID-19
Authors: Le Balc'h P, Pinceaux K, Pronier C, Seguin P, Reizine F PMID: 32859241 PMCID: PMC7453668 DOI: 10.1186/s13054-020-03252-3 Abstract The SARS-CoV-2 infection can lead to severe acute respiratory distress syndrome (ARDS) with prolonged mechanical ventilation (MV). Patients with coronavirus disease 2019 (COVID-19) associated ARDS usually met the diagnosis criteria for sepsis-associated immunosuppression as acquired infections, [...]
Categories: I-RECOVER Post-Vaccine, MATH+
Authors: Buijsers B, Yanginlar C, Maciej-Hulme ML, de Mast Q PMID: 32853989 PMCID: PMC7445140 DOI: 10.1016/j.ebiom.2020.102969 Abstract Coronavirus disease-2019 (COVID-19) is associated with severe inflammation in mainly the lung, and kidney. Reports suggest a beneficial effect of the use of heparin/low molecular weight heparin (LMWH) on mortality in COVID-19. In part, this beneficial effect could [...]
Categories: MATH+
Tags: COVID-19
Authors: Vatsalya V, Li F, Frimodig J, Gala KS, Srivastava S, Kong M PMID: 32869036 PMCID: PMC7457607 DOI: 10.1101/2020.08.23.20177501 Abstract Introduction Emerging infectious diseases, especially the coronavirus disease identified in 2019 (COVID-19), can be complicated by a severe exacerbation in the Th17 cell-mediated IL-17 proinflammatory immune storm. This enhanced immune response plays a major role [...]
Categories: MATH+
Authors: Cypel M, Keshavjee S PMID: 32857989 PMCID: PMC7447224 DOI: 10.1016/S2213-2600(20)30393-3 Abstract Several respiratory viruses are known to cause acute respiratory distress syndrome (ARDS). Survival and lung recovery rates are well known for influenza viruses; however, ARDS related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has posed an unprecedented challenge. Lung transplantation has [...]
Categories: MATH+
Tags: COVID-19