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Authors: Avendano-Sola C, Ramos-Martinez A, Munez-Rubio E, Ruiz-Antoran B, de Molina RM PMID: 34473652 PMCID: PMC8516461 DOI: 10.1172/JCI152740 Abstract BACKGROUND. Passive immunotherapy with convalescent plasma (CP) is a potential treatment for COVID-19. Evidence from controlled clinical trials is inconclusive. METHODS. We conducted a randomized, open-label, controlled clinical trial at 27 hospitals in Spain. Patients had [...]
Categories: MATH+
Tags: Convalescent Plasma, COVID-19
Authors: Janiaud P, Axfors C, Schmitt AM, Glory V, Moher D PMID: 33635310 PMCID: PMC7911095 DOI: 10.1001/jama.2021.2747 Abstract Importance: Convalescent plasma is a proposed treatment for COVID-19. Objective: To assess clinical outcomes with convalescent plasma treatment vs placebo or standard of care in peer-reviewed and preprint publications or press releases of randomized clinical trials (RCTs). [...]
Categories: MATH+
Tags: Convalescent Plasma, COVID-19
Authors: Thompson MA, Henderson JP, Shah PK, Rubenstein SM, Joyner MJ, Flora DB. doi: https://doi.org/10.1101/2021.02.05.21250953 Abstract Convalescent plasma may benefit immunocompromised individuals with COVID-19, including those with hematologic malignancy. We evaluated the association of convalescent plasma treatment with 30-day mortality in hospitalized adults with hematologic malignancy and COVID-19 from a multi-institutional cohort. 143 treated patients [...]
Categories: MATH+
Tags: Convalescent Plasma, COVID-19
Authors: Li L, Zhang W, Hu Y, Tong X, Zeng S, Yang J PMID: 32492084 PMCID: PMC7270883 DOI: 10.1001/jama.2020.10044 Abstract Importance: Convalescent plasma is a potential therapeutic option for patients with coronavirus disease 2019 (COVID-19), but further data from randomized clinical trials are needed. Objective: To evaluate the efficacy and adverse effects of convalescent plasma [...]
Categories: MATH+
Tags: Convalescent Plasma, COVID-19