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Authors: Parhiz H, Brenner JS, Patel PN, Papp TE, Li Q, Shi R PMID: 34953981 PMCID: PMC8695324 DOI: 10.1016/j.jconrel.2021.12.027 Abstract Current nucleoside-modified RNA lipid nanoparticle (modmRNA-LNP) technology has successfully paved the way for the highest clinical efficacy data from next-generation vaccinations against SARS-CoV-2 during the COVID-19 pandemic. However, such modmRNA-LNP technology has not been characterized [...]
Categories: I-RECOVER Post-Vaccine
Tags: Inflammation Exacerbation, mRNA
Authors: Ndeupen S, Qin Z, Jacobsen S, Bouteau A, Estanbouli H, Igyarto BZ PMID: 34841223 PMCID: PMC8604799 DOI: 10.1016/j.isci.2021.103479 Abstract Vaccines based on mRNA-containing lipid nanoparticles (LNPs) are a promising new platform used by two leading vaccines against COVID-19. Clinical trials and ongoing vaccinations present with varying degrees of protection levels and side effects. However, [...]
Categories: I-RECOVER Post-Vaccine
Tags: Inflammation, mRNA