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  • Reference: Aggregating platelets contract isolated canine pulmonary arteries by releasing 5-hydroxytryptamine.

    Published On: September 1, 1984

    Authors: McGoon MD, Vanhoutte PM PMID: 6470141 PMCID: PMC425237 DOI: 10.1172/JCI111499 Abstract To examine the effect of platelets and 5-hydroxytryptamine on pulmonary arterial smooth muscle, rings of canine pulmonary arteries, with and without endothelium, were studied under isometric conditions in physiological salt solution. 5-Hydroxytryptamine, but not the thromboxane-like endoperoxide analogue U-46619, produced concentration-dependent contractions of [...]

    Categories: MATH+

    Tags: pulm