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Authors: Kou X, Chen N PMID: 28837083 PMCID: PMC5622687 DOI: 10.3390/nu9090927 Abstract Alzheimer's disease (AD) is one of the most common neurodegenerative disorders over the age of 65 years old. Although several underlying mechanisms for explaining the pathogenesis of AD are elucidated, the effective supplements or drugs for the intervention of AD are still limited. [...]
Categories: I-RECOVER Long Covid, I-RECOVER Post-Vaccine
Tags: alzheimers, autophagy, resveratrol
Authors: Park D, Jeong H, Lee MN, Koh A, Kwon O, Yang YR et al. PMID: 26902888 PMCID: PMC4763238 DOI: 10.1038/srep21772 Abstract Resveratrol (RSV) is a natural polyphenol that has a beneficial effect on health, and resveratrol-induced autophagy has been suggested to be a key process in mediating many beneficial effects of resveratrol, such as [...]
Categories: I-RECOVER Long Covid, I-RECOVER Post-Vaccine
Tags: autophagy, resveratrol
Authors: Morselli E, Marino G, Bennetzen MV, Eisenberg T, Megalou E, Schroeder S et al. PMID: 21339330 PMCID: PMC3044119 DOI: 10.1083/jcb.201008167 Abstract Autophagy protects organelles, cells, and organisms against several stress conditions. Induction of autophagy by resveratrol requires the nicotinamide adenine dinucleotide-dependent deacetylase sirtuin 1 (SIRT1). In this paper, we show that the acetylase inhibitor [...]
Categories: I-RECOVER Long Covid, I-RECOVER Post-Vaccine
Tags: autophagy, resveratrol, spermidine
Authors: Walle T PMID: 21261636 DOI: 10.1111/j.1749-6632.2010.05842.x Abstract This paper reviews our current understanding of the absorption, bioavailability, and metabolism of resveratrol, with an emphasis on humans. The oral absorption of resveratrol in humans is about 75% and is thought to occur mainly by transepithelial diffusion. Extensive metabolism in the intestine and liver results in [...]
Categories: I-RECOVER Long Covid, I-RECOVER Post-Vaccine
Tags: resveratrol
Authors: Morselli E, Galluzzi L, Kepp O, Criollo A, Maiuri MC, Madeo F PMID: 20157579 PMCID: PMC2815753 DOI: 10.18632/aging.100110 Abstract Although autophagy has widely been conceived as a self-destructive mechanism that causes cell death, accumulating evidence suggests that autophagy usually mediates cytoprotection, thereby avoiding the apoptotic or necrotic demise of stressed cells. Recent evidence produced [...]
Categories: I-RECOVER Long Covid, I-RECOVER Post-Vaccine
Tags: autophagy, resveratrol, spermidine