Auhtors: Fridman WH, Pagès F, Sautès-Fridman C, Galon J

PMID: 22419253 DOI: 10.1038/nrc3245

Abstract

Tumours grow within an intricate network of epithelial cells, vascular and lymphatic vessels, cytokines and chemokines, and infiltrating immune cells. Different types of infiltrating immune cells have different effects on tumour progression, which can vary according to cancer type. In this Opinion article we discuss how the context-specific nature of infiltrating immune cells can affect the prognosis of patients.

Keywords: immune contexture, tumor, immune cells

More on: Cancer Care

More on: Tumor